Derivatization reagents for gas chromatography and organic synthesis.

The protection of polar groups such as carboxylic acids, alcohols and amines with suitable reagents to produce non-polar derivatives, is of great interest in gaschromatography and in organic synthesis. By changing the properties of a sample, it can be made more stable and easier to separate and detect by gaschromatography. A suitable reagent should offer:

ease of reaction
quantitative reaction
reproducible yields and results
no side reactions
generation of a stable product
higher volatility of the derivative
lower detection limit
enabling of special detection methods (e.g. ECD for fluorine containing derivatives)
Alkylations, acylations and silylations are the most common reactions to derivatize a substrate. Acros Organics is proud to bring you the following reagents commonly used for these derivatizations: